Abstract
Even though psoriasis is a common skin disorder, reports of it involving the oral cavity are exceedingly rare, with less than 100 publications in the literature. Biopsy-proven oral psoriasis has been reported in the oral medical literature, but the commonest oral mucosal findings in most studies are associated non-specific features including fissured and geographic tongue. Case series on this entity have not provided any definitive data to support its existence. From the evidence available to date, it is still unclear if oral psoriasis is a distinct entity or if, indeed, it exists.
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References
Allen M, Ishida-Yamamoto A, McGrath J, Davison S, Iizuka H, Simon M, Guerrin M, Hayday A, Vaughan R, serre G, Trembath R, Barker J (2001) Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders. Lab Invest 81:969–976
Ariyawardana A, Tilakaratne WM, Ranasinghe AW, Dissanayake M (2004) Oral psoriasis in an 11-year-old child: a case report. Int J Paediatr Dent 14:141–145
Baker H, Ryan TJ (1968) Generalised pustular psoriasis. A clinical and epidemiological study of 104 cases. Br J Dermatol 80:771–793
Binmadi NO, Jham BC, Meiller TF, Scheper MA (2010) A case of a deeply fissured tongue. Oral Surg Oral Med Oral Pathol Oral Rad 109:659–663
Brenner S, Lipitz R, Ilie B, Krakowski A (1982) Psoriasis of the lips: the unusual Koebner phenomenon caused by protruding upper teeth. Dermatologica 164:413–416
Bruce AJ, Rogers RS (2003) Oral psoriasis. Dermatol Clin 21:99–104
Büchner A, Begleiter A (1976) Oral lesions in psoriatic patients. Oral Surg Oral Med Oral Pathol 41:327–332
Costa SC, Hirota SK, Takahashi MD, Andrade H Jr, Migliari DA (2009) Oral lesions in 166 patients with cutaneous psoriasis: a controlled study. Med Oral Pathol Oral Cir Bucal 14:e371–e375
Daneshpazhooh M, Moslehi H, Akhyani M, Etesami M (2004) Tongue lesions in psoriasis: a controlled study. BMC Dermatology 4:16
Dawson TA (1974) Tongue lesions in generalised pustular psoriasis. Br J Dermatol 91:419–424
DeGregori G, Pippen R, Davies E (1971) Psoriasis of the gingiva and the tongue: report of a case. J Periodontol 42:97–100
Dendy RA, Walker GB, Harrison PV (1985) The buccal mucosa in erythrodermic psoriasis. Clin Exp Dermatol 10:495–498
Eastman JR, Goldblatt LI (1983) Psoriasis. Palatal manifestations and physiological considerations. J Periodontol 54:736–739
Eidelman E, Chosack A, Cohen T (1976) Scrotal tongue and geographic tongue: polygenic and associated traits. Oral Surg Oral Med Oral Pathol 42:591–596
Elliott JR, Bowers GM, Corio RL (1985) The clinical problem of oral psoriasis. Ear Nose Throat J 64:223–227
Espelid M, Bang G, Johannessen AC, Leira JI, Christensen O (1991) Geographic stomatitis: report of 6 cases. J Oral Pathol Med 20:425–428
Gonzaga HF, Torres EA, Alchorne MM, Gerbase-Delima M (1996) Both psoriasis and benign migratory glossitis are associated with HLA-Cw6. Br J Dermatol 135:368–370
Griffiths CEM, Barker JNWN (2007) Pathogenesis and clinical features of psoriasis. Lancet 21:263–271
Gul U, Kilic A, Gonul M, Soylu S, Bilgili S, Han O (2006) Psoriasis of the lips: an unusual localization. Int J Dermatol 45:1381–1382
Hernandez-Perez F, Jaimes-Aveldanez A, Urquizo-Ruvalcaba Mde L, Diaz-Barcelot M, Irigoyen-Camacho ME, Vega-Memije E, Mosqueda-Taylor A (2008) Prevalence of oral lesions in patients with psoriasis. Med Oral Patol Oral Cir Bucal 13:E703–E708
Hietanen J, Salo OP, Kanerva L, Juvakoski T (1984) Study of oral mucosa in 200 consecutive patients with psoriasis. Scand J Dent Res 92:50–54
Kaur I, Handa S, Kumar B (1997) Oral lesions in psoriasis. Int J Dermatol 36:78–79
Lier GC, Mrowietz U, Wolfart M, Warnke PH, Wiltfang J, Springer IN (2009) Psoriasis of the tongue. J Craniomaxillofac Surg 37:51–53
Migliari DA, Penha SS, Marques MM, Matthews RW (2004) Considerations on the diagnosis of oral psoriasis: a case report. Med Oral 9:300–303
Morris LF, Philips CM, Binnie WH, Sander HM, Silverman AK, Menter MA (1992) Oral lesions in patients with psoriasis: a controlled study. Cutis 49:339–344
Nograles KE, Davidovici B, Krueger JG (2010) New insights in the immunologic basis of psoriasis. Semin Cutan Med Surg 29:3–9
Novak N, Gros E, Bieber T, Allam JP (2010) Human skin and oral mucosal dendritic cells as ‘good guys’ and ‘bad guys’ in allergic immune responses. Clin Exp Immunol 161:28–33
Novak N, Haberstok J, Bieber T, Allam JP (2008) The immune privilege of the oral mucosa. Trends Mol Med 14:191–198
Pisanty S, Ship II (1970) Oral psoriasis. Oral Surg Oral Med Oral Pathol 30:351–355
Pogrel MA, Cram D (1998) Intraoral findings in patients with psoriasis with a special reference to ectopic geographic tongue (erythema circinata). Oral Surg Oral Med Oral Pathol 66:184–189
Rahman MA, Fikree M (2000) Perioral psoriasis. J Eur Acad Dermatol Venereol 14:521–522
Reibel J, Clausen H, Dale BA, Thacher S (1989) Immunohistochemical analysis of stratum corneum components in oral squamous epithelia. Differentiation 41:237–244
Richardson LJ, Kratochvil FJ, Zieper MB (2000) Unusual palatal presentation of oral psoriasis. J Can Dent Assoc 66:80–82
Robinson CM, Di Biase AT, Leigh IM, Williams DM, Thornhill M (1996) Oral psoriasis. Br J Dermatol 134:347–349
Salmon TN, Robertson GR Jr, Tracy NH, Hiatt WR (1974) Oral psoriasis. Oral Surg Oral Med Oral Pathol 38:48–54
Sklavounou A, Laskaris G (1990) Oral psoriasis: report of a case and review of the literature. Dermatologica 180:157–159
Tosti A, Misciali C, Cameli N, Vincenzi C (2001) Guess what! Psoriasis of the lips. Eur J Dermatol 11:589–590
Ulmansky M, Michelle R, Azaz B (1995) Oral psoriasis: report of six new cases. J Oral Pathol Med 24:42–45
van der Wal N, van der Kwast WA, van Dijk E, van der Waal I (1988) Geographic stomatitis and psoriasis. Int J Oral Maxillofac Surg 17:106–109
Weathers DR, Baker G, Archard HO, Burkes EJ Jr (1974) Psoriasiform lesions of the oral mucosa (with emphasis on “ectopic geographic tongue”). Oral Surg Oral Med Oral Pathol 37:872–888
Yamada J, Amar S, Petrungaro P (1992) Psoriasis-associated periodontitis: a case report. J Periodontol 63:854–857
Yamamoto T, Nishioka K (2002) Oral psoriasis in a patient with hepatitis C virus. Eur J Dermatol 12:75–76
Younai FS, Phelan JA (1997) Oral mucositis with features of psoriasis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 84:61–67
Zhu JF, Kaminski MJ, Pulitzer DR, Hu J, Thomas HF (1996) Psoriasis: pathophysiology and oral manifestations. Oral Dis 2:135–144
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Acknowledgments
RBW is an NIHR Clinical Senior Lecturer. CEMG is partly supported by the NIHR Manchester Biomedical Research Centre.
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There are no competing interests for any of the authors in preparing this manuscript.
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Yesudian, P.D., Chalmers, R.J.G., Warren, R.B. et al. In search of oral psoriasis. Arch Dermatol Res 304, 1–5 (2012). https://doi.org/10.1007/s00403-011-1175-3
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DOI: https://doi.org/10.1007/s00403-011-1175-3