Skip to main content
Log in

Reply to: Rapid antidepressant effects and abuse liability of ketamine

  • Letter to Editor
  • Published:
Psychopharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Hillhouse T, Porter J, Negus SS (2014) Dissociable effects of the noncompetitive NMDA receptor antagonists ketamine and MK-801 on intracranial self-stimulation in rats. Psychopharmacology (Berlin). doi:10.1007/s00213-014-3451-3

    Google Scholar 

  • Hustveit O, Maurset A, Øye I (1995) Interaction of the chiral forms of ketamine with opioid, phencyclidine, σ and muscarinic receptors. Pharmacol Toxicol 77:355–359

    Article  PubMed  CAS  Google Scholar 

  • McCambridge J, Winstock A, Hunt N, Mitcheson L (2007) 5-Year trends in use of hallucinogens and other adjunct drugs among UK dance drug users. Eur Addict Res 13:57–64

    Article  PubMed  Google Scholar 

  • Oye I, Paulsen O, Maurset A (1992) Effects of ketamine on sensory perception: evidence for a role of N-methyl-d-aspartate receptors. J Pharmacol Exp Ther 260:1209–1213

    PubMed  CAS  Google Scholar 

  • Rocha BA, Ward AS, Egilmez Y, Lytle DA, Emmett-Oglesby MW (1996) Tolerance to the discriminative stimulus and reinforcing effects of ketamine. Behav Pharmacol 7:160–168

    PubMed  CAS  Google Scholar 

  • Shek DTL (2007) Tackling adolescent substance abuse in Hong Kong: where we should and should not go. Sci World J 7:2021–2030

    Article  Google Scholar 

  • Suzuki T, Kato H, Aoki T, Tsuda M, Narita M, Misawa M (2000) Effects of the non-competitive NMDA receptor antagonist ketamine on morphine-induced place preference in mice. Life Sci 67:383–389

    Article  PubMed  CAS  Google Scholar 

  • Vollenweider FX, Leenders KL, Øye I, Hell D, Angst J (1997) Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET). Eur Neuropsychopharmacol 7:25–38

    Article  PubMed  CAS  Google Scholar 

  • Zeilhofer HU, Swandulla D, Geisslinger G, Brune K (1992) Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons. Eur J Pharmacol 213:155–158

    Article  PubMed  CAS  Google Scholar 

  • Zhang J-C, Li S-X, Hashimoto K (2014) R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine. Pharmacol Biochem Behav 116:137–141

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This research was supported by NIH grant R01 NS070715.

Conflict of interest

None declared.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Stevens Negus.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hillhouse, T.M., Porter, J.H. & Negus, S.S. Reply to: Rapid antidepressant effects and abuse liability of ketamine. Psychopharmacology 231, 2043–2044 (2014). https://doi.org/10.1007/s00213-014-3544-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00213-014-3544-z

Keywords

Navigation