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Surviving life-threatening MDMA (3,4-methylenedioxymethamphetamine, ecstasy) toxicity caused by ritonavir (RTV)

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References

  1. Yubero-Lahoz S, Pardo R, Farré M, O’Mahony B, Torrens M, Mustata C, Pérez-Mañá C, Carbó ML, de la Torre R (2011) Sex differences in 3,4-methylenedioxymethamphetamine (MDMA; ecstasy)-induced cytochrome P450 2D6 inhibition in humans. Clin Pharmacokinet 50:319–329

    Article  PubMed  CAS  Google Scholar 

  2. Henry JA, Hill IR (1998) Fatal interaction between ritonavir and MDMA. Lancet 352:1751–1752

    Article  PubMed  CAS  Google Scholar 

  3. Harrington RD, Woodward JA, Hooton TM, Horn JR (1999) Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate. Arch Intern Med 159:2221–2224

    Article  PubMed  CAS  Google Scholar 

  4. de la Torre R, Farré M, Ortuño J, Mas M, Brenneisen R, Roset PN, Segura J, Camí J (2000) Non-linear pharmacokinetics of MDMA (‘ecstasy’) in humans. Br J Clin Pharmacol 49:104–109

    Article  PubMed  Google Scholar 

  5. O’Mathúna B, Farré M, Rostami-Hodjegan A, Yang J, Cuyàs E, Torrens M, Pardo R, Abanades S, Maluf S, Tucker GT, de la Torre R (2008) The consequences of 3,4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans. J Clin Psychopharmacol 28:523–529

    Article  PubMed  Google Scholar 

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Acknowledgments

This work was supported by grants from DIUE de la Generalitat de Catalunya (2009 SGR 718), ISCIII-FEDER-FIS-RTA RD06/0001/1009 and ISCIII-FIS-CAIBER CAI08/01/0024.

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Authors and Affiliations

  1. Human Pharmacology and Clinical Neurosciences Research Group, Neurosciences Research Program, IMIM-Hospital del Mar Research Institute, Barcelona, Spain

    Esther Papaseit, Clara Pérez-Mañá, Mitona Pujadas, Rafael de la Torre & Magí Farré

  2. Intensive Care Unit, Hospital del Mar, Barcelona, Spain

    Antonia Vázquez & Joan Nolla

  3. Department of Experimental and Health Sciences-CEXS-(UPF), Barcelona, Spain

    Rafael de la Torre & Joan Nolla

  4. Department of Pharmacology, Therapeutics and Toxicology, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

    Esther Papaseit, Clara Pérez-Mañá & Magí Farré

Authors
  1. Esther Papaseit
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  2. Antonia Vázquez
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  3. Clara Pérez-Mañá
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  4. Mitona Pujadas
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  5. Rafael de la Torre
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  6. Magí Farré
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  7. Joan Nolla
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Corresponding author

Correspondence to Esther Papaseit.

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Papaseit, E., Vázquez, A., Pérez-Mañá, C. et al. Surviving life-threatening MDMA (3,4-methylenedioxymethamphetamine, ecstasy) toxicity caused by ritonavir (RTV). Intensive Care Med 38, 1239–1240 (2012). https://doi.org/10.1007/s00134-012-2537-9

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  • DOI: https://doi.org/10.1007/s00134-012-2537-9

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