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Reduction of biological substances by water-soluble phosphines: Gamma-globulin (IgG)

  • Specialia
  • Chimica. Biochimica. Biophysica
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Résumé

Deux composés polypeptides sont formés par la réduction de la gamma-globuline par des phosphines tertiaires hydrosolubles; réduction qui s'opère à de plus faibles concentrations des phosphines que du 2-mercaptoéthanol. Avec ces 2 méthodes, les produits de la réaction sont comparables. De plus, les phosphines peuvent inactiver le facteur rheumatoïde, tel que le révèle l'agglutination au latex.

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Authors and Affiliations

  1. Department of Medicine and Department of Biochemistry, State University of New York, Downstate Medical Center, 11203, Brooklyn, New York, USA

    M. E. Levison, A. S. Josephson & D. M. Kirschenbaum

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  1. M. E. Levison
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  2. A. S. Josephson
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  3. D. M. Kirschenbaum
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Levison, M.E., Josephson, A.S. & Kirschenbaum, D.M. Reduction of biological substances by water-soluble phosphines: Gamma-globulin (IgG). Experientia 25, 126–127 (1969). https://doi.org/10.1007/BF01899076

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  • DOI: https://doi.org/10.1007/BF01899076

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