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Refined regional assignment of the human tissue factor pathway inhibitor (TFPI) gene to chromosome band 2q32 by non-isotopic in situ hybridization

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Summary

The potential usefulness of the tissue factor pathway inhibitor gene for construction of physical and genetic linkage maps of chromosome 2 is reported.

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References

  • Broze GJ Jr, Warren LA, Novotny WF, Higuchi DA, Girard TJ, Miletich JP (1988) The lipoprotein-associated coagulation inhibitor that ihibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action. Blood 71:335

    Google Scholar 

  • Girard TJ, Warren LA, Novotny WF, Bejcek BE, Miletich JP, Broze GJ Jr (1989) Identification of the 1. 4kb and 4. 0kb messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein. Thromb Res 55:37

    Google Scholar 

  • Girard TJ, Eddy R, Wesselschmidt RL, Macphail LA, Likert KM, Byers MG, Shows TB, Broze GJ Jr (1990) Structure of the human lipoprotein-associated coagulation inhibitor gene: intron/exon organization and localization of the gene to chromosome 2. Blood 76:421a

  • Girard TJ, Eddy R, Wesselschmidt RL, Macphail LA, Likert KM, Byers MG, Shows TB, Broze GJ Jr (1991) Structure of the human lipoprotein-associated coagulation inhibitor gene. J Biol Chem 266:5036

    Google Scholar 

  • Landegent JE, Jansen in de Wal N, Dirks RW, Baas F, Ploeg M van der (1987) Use of whole cosmid cloned genomic sequences for chromosomal localisation by non-radioactive in situ hybridization. Hum Genet 77:366

    Google Scholar 

  • Van der Logt CPE, Reitsma PH, Bertina RM (1990) A PstI RFLP of the LACI gene. Nucleic Acids Res 18:5920

    Google Scholar 

  • Van der Logt CPE, Reitsma PH, Bertina RM (1991) Intron-exon organization of the human gene coding for the lipoprotein-associated coagulation inhibitor: the factor Xa dependent inhibitor of the extrinsic pathway of coagulation. Biochemistry 30:1571

    Google Scholar 

  • Wiegant J, Galjart NJ, Raap AK, d'Azzo A (1991) The gene encoding human protective protein (PPGB) is on chromosome 20. Genomics 10:345

    Google Scholar 

  • Wun TC, Kretzmer KK, Girard TJ, Miletich JP, Broze GJ Jr (1988) Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains. J Biol Chem 263:6001

    Google Scholar 

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Van der Logt, C.P.E., Kluck, P.M.C., Wiegant, J. et al. Refined regional assignment of the human tissue factor pathway inhibitor (TFPI) gene to chromosome band 2q32 by non-isotopic in situ hybridization. Hum Genet 89, 577–578 (1992). https://doi.org/10.1007/BF00219189

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  • DOI: https://doi.org/10.1007/BF00219189

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