Abstract
We have cloned and sequenced the human θ1-globin gene. The nucleotide sequence and organization of the human θ1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan θ1-globin gene. If these genes are functional, the sequences of their θ1-globin chains would differ by only one amino acid residue (at position 137).
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This research was supported by USPHS Research Grants HLB-05168 and HLB-15158. This is contribution No. 1085 from the Department of Cell and Molecular Biology at the Medical College of Georgia in Augusta.
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Gonzalez-Redondo, J.M., Han, I.S., Gu, Y.C. et al. Nucleotide sequence of the humanθ 1-globin gene. Biochem Genet 26, 207–211 (1988). https://doi.org/10.1007/BF00561460
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DOI: https://doi.org/10.1007/BF00561460