Skip to main content
Log in

GART, SON, IFNAR, and CRF2-4 genes cluster on human Chromosome 21 and mouse Chromosome 16

  • Short Communications
  • Published:
Mammalian Genome Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Berdichevskii, F.B., Chumakov, I.M., and Kiselev, L.L. (1988). Determination of the nucleotide sequence of the son3 fragment of the human genome: identification of a new protein with an unusual structure and homology with DNA-binding proteins. Mol. Biol. (Engl.) 22, 639–646.

    Google Scholar 

  • Bird, A.P. (1987). CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3, 342–347.

    Google Scholar 

  • Bird, A.P. (1989). Two classes of observed frequency for rare-cutter sites in CpG islands. Nucleic Acids Res. 17, 9485.

    Google Scholar 

  • Brownstein, B.H., Silverman, G.A., Little, R.D., Burke, D.T., Korsmeyer, S.J., Schlessinger, D., and Olson, M.V. (1989). Isolation of single-copy human genes from a library of yeast artificial chromosome clones. Science 244, 1348–1351.

    Google Scholar 

  • Chadefaux, B., Allard, D., Rethore, M.O., Raoul, O., Poissonnier, M., Gilgenkrantz, S., Cheruy, C., and Jerome, H. (1984). Assignment of human phosphoribosylglycinamide synthetase locus to region 21q22.1. Hum. Genet. 66, 190–192.

    Google Scholar 

  • Cox, D.R. and Epstein, C.J. (1985). Comparative gene mapping of human chromosome 21 and mouse chromosome 16. In Molecular Structure of the Number 21 Chromosome and Down Syndrome, G.F. Smith, ed. (New York: New York Academy of Sciences), pp. 169–177.

    Google Scholar 

  • Cox, D.R., Epstein, L.B., and Epstein, C.J. (1980). Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to chromosome 16. Proc. Natl. Acad. Sci. USA 77, 2168–2172.

    Google Scholar 

  • Cox, D.R., Goldblatt, D., and Epstein, C.J. (1981). Chromosomal assignment of mouse PRGS: further evidence for homology between mouse chromosome 16 and human chromosome 21. Am. J. Hum. Genet. 33, 145A.

  • Davisson, M.T., Lalley, P.A., Petters, J., Doolittle, D.P., Hillyard, A.L., and Searle, A.G. (1990a). Report of the comparative subcommittee for human and mouse homologies. Cytogenet. Cell Genet. 55, 434–456.

    Google Scholar 

  • Davisson, M.T., Schmidt, C., and Akeson, E.C. (1990b). Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome. In Molecular Genetics of Chromosome 21 and Down Syndrome, D. Patterson and C.J. Epstein, eds. (New York: Wiley-Liss, Inc.) pp. 263–280.

    Google Scholar 

  • Epstein, C.J., Cox, D.R., and Epstein, L.B. (1985). Mouse trisomy 16: an animal model of human trisomy 21 (Down syndrome). In Molecular Structure of the Number 21 Chromosome and Down Syndrome, G.F. Smith, ed. (New York: New York Academy of Sciences), pp. 157–168.

    Google Scholar 

  • Feinberg, A.P. and Vogelstein, B. (1984). Addendum to ‘A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity’. Anal. Biochem. 137, 266–267.

    Google Scholar 

  • Francke, U. and Taggart, R.T. (1979). Assignment of the gene for cytolasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of HPRT to a region of the X chromosome in the mouse. Proc. Natl. Acad. Sci. USA 76, 5230–5233.

    Google Scholar 

  • Gardiner, K., Laas, W., and Patterson, D. (1986). Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis. Somatic Cell Mol. Genet. 12, 185–195.

    Google Scholar 

  • Gardiner, K., Watkins, P., Munke, M., Drabkin, H., Jones, C., and Patterson, D. (1988). Partial physical map of human chromosome 21. Somatic Cell Mol. Genet. 14, 623–628.

    Google Scholar 

  • Gardiner, K. (1990). Physical mapping of the long arm of chromosome 21. In Molecular Genetics of Chromosome 21 and Down Syndrome, C.J. Epstein, ed. (New York: Wiley-Liss, Inc.) pp. 1–14.

    Google Scholar 

  • Gardiner, K., Horisberger, M., Kraus, J., Tantravahi, U., Korenberg, J., Rao, V., Reddy, S., and Patterson, D. (1990). Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions. EMBO J. 9, 25–34.

    Google Scholar 

  • Horisberger, M.A., Wathelet, M., Szpirer, C., Islam, Q., Levan, G., Huez, G., and Content, J. (1988). cDNA cloning and assignment to chromosome 21 of IFI-78K gene, the human equivalent of murine Mx gene. Somat. Cell Mol. Genet. 14, 123–131.

    Google Scholar 

  • Howley, P.M., Israel, M.A., Law, M.-F., and Martin, M.A. (1979). A rapid method for detecting and mapping homology between heterologous DNAs. J. Biol. Chem. 254, 4876–4883.

    Google Scholar 

  • Korenberg, J.R., Kawashima, H., Pulst, S.-M., Ikeuchi, T., Ogasawara, N., Magenis, E., Ikawa, K., Taniguchi, N. and Epstein, C.J. (1990). Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype. Am. J. Hum. Genet. 47, 236–246.

    Google Scholar 

  • Lejeune, J., Gauthier, M., and Turpin, R. (1959). Etudes des chromosomes somatiques de neuf enfants mongolients. C. R. Seances Acad. Sci. [III] 248, 1721–1722.

    Google Scholar 

  • Lin, P.-F., Slate, D.L., Lawyer, F.C., and Ruddle, F.H. (1980). Assignment of the murine interferon sensitivity and cytoplasmic superoxide dismutase genes to chromosome 16. Science 209, 285–287.

    Google Scholar 

  • Lutfalla, G., Roeckel, N., Mogensen, K.E., Mattei, M.-G., and Uze, G. (1990). Assignment of the human interferon-a receptor gene to chromosome 21q22.1 by in situ hybridization. J. Interferon Res. 10, 515–517.

    Google Scholar 

  • Lutfalla, G., Gardiner, K., Proudhon, D., Vielh, E., and Uze, G. (1992). The structure of the human interferon α/β receptor gene. J. Biol. Chem. 267, 2802–2809.

    Google Scholar 

  • Lutfalla, G., Gardiner, K., and Uze, G. (1993). A new member of the cytokine receptor gene family maps on chromosome 21 at 35 kb from IFNAR. Genomics, in press.

  • Rahmani, Z., Blouin, J.-L., Creau-Goldberg, N., Watkins, P.C., Mattei, J.-F., Poissonnier, M., Prieur, M., Chettouh, Z., Nicole, A., Aurias, A., Sinet, P.-M., and Delabar, J.-M. (1989). Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome. Proc. Natl. Acad. Sci. USA 86, 5958–5962.

    Google Scholar 

  • Reeves, R.H., Gearhart, J.D., and Littlefield, J.W. (1986). Genetic basis for a mouse model of Down Syndrome. Brain Res. Bull. 16, 803–814.

    Google Scholar 

  • Reeves, R.H., Gallahan, D., O'Hara, B.F., Callahan, R., and Gearhart, J.D. (1987). Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16. Cytogenet. Cell Genet. 44, 76–81.

    Google Scholar 

  • Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press.

    Google Scholar 

  • Staeheli, P., Pravtcheva, D., Lundin, L.-G., Acklin, M., Ruddle, F., Lindenmann, F., and Haller, O. (1986). Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16. J. Virol. 58, 967–969.

    Google Scholar 

  • Tassone, F., Cheng, S., and Gardiner, K. (1992). Analysis of chromosome 21 yeast artificial chromosome (YAC) clones. Am. J. Hum. Genet. 51, 1251–1264.

    Google Scholar 

  • Uze, G., Lutfalla, G., Bander, M-T., Proudhon, D., and Morgensen, K.E. (1992). Behavior of a cloned murine interferon α/β receptor expressed in homospecific and heterospecific background. Proc. Natl. Acad. Sci. USA 89, 4774–4778.

    Google Scholar 

  • Watson, D.K., McWilliams-Smith, M.J., Kozak, C., Reeves, R., Gearhart, J., Nunn, M.F., Nash, W., Fowle, J.R.I., Duesberg, P., Papas, T.S., and O'Brien, S.J. (1986). Conserved chromosomal positions of dual domains of the ets protooncogene in cats, mice, and humans. Proc. Natl. Acad. Sci. USA 83, 1792–1796.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cheng, S., Lutfalla, G., Uze, G. et al. GART, SON, IFNAR, and CRF2-4 genes cluster on human Chromosome 21 and mouse Chromosome 16. Mammalian Genome 4, 338–342 (1993). https://doi.org/10.1007/BF00357094

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00357094

Keywords

Navigation