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Assignment of a human beta-crystallin gene to 17cen-q23

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Summary

The gene map assignment of a human beta-crystallin gene to 17cen-q23 has been made using a bovine probe in the study of human-mouse and human-Chinese hamster somatic cell hybrids containing parts of human chromosome 17.

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References

  • Carper D, Shinohara T, Piatigorsky J, Kinoshita JH (1982) Deficiency of functional messenger RNA for a developmentally regulated B-crystallin polypeptide in a hereditary cataract. Science 217: 463–464

    Google Scholar 

  • Davidson RL, Gerald PS (1976) Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol. Somatic Cell Genet 2: 165–176

    Google Scholar 

  • Feinberg AP, Vogelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity Anal Biochem 132: 6–13

    Google Scholar 

  • Fodor EJB, Doty P (1977) Highly specific transcription of globin sequences in isolated reticulocyte nuclei. Biochem Biophys Res Commun 77: 1478–1485

    Google Scholar 

  • Gorin MB, Horwitz J (1984) Cloning and characterization of a cow beta-crystallin cDNA. Curr Eye Res 3: 939–948

    Google Scholar 

  • Kucherlapati RS, Baker RM, Ruddle FH (1975) Ouabain as a selective agent in the isolation of somatic cell hybrids. Cytogenet Cell Genet 14: 326–363

    Google Scholar 

  • Law ML, Cai GY, Kao FT, Hogg D, Breitman M, Tsui LC (1985) Localization of a human beta-crystallin gene (CRY B1) to the long arm of chromosome 17. (8th International Workshop on Human Gene Mapping.) Cytogenet Cell Genet 40: 677

    Google Scholar 

  • Littlefield JW (1964) Selection of hybrids from matings of fibroblasts in vitro and their preserved recombinants. Science 145: 709–710

    Google Scholar 

  • Mohandas T, Sparkes RS, Sparkes MC, Shulkin JD, Toomey K, Funderburk SJ (1979) Regional localization of human gene loci on chromosome 9: studies of somatic cell hybrids containing human translocations. Am J Hum Genet 31: 586–600

    Google Scholar 

  • Mohandas T, Sparkes RS, Suh EJ, Hershfield MS (1984) Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen-q131) and adenosine deaminase (q131-qter) on chromosome 20. Hum Genet 66: 292–295

    Google Scholar 

  • Piatigorsky J (1984) Lens crystallins and their gene families. Cell 38: 620–621

    Google Scholar 

  • Piatigorsky J, Nickerson JM, King CR, Inana G, Hejtmancik JF, Hawkins JW, Borras T, Shinohara T, Wistow G, Norman B (1984) Crystallin genes: templates for lens transparency. In: Nugent J, Whelan J (eds) Human cataract formation. (Ciba Foundation Symposium 106) Pitman, London, pp 191–207

    Google Scholar 

  • Schoenmakers JGG, den Dunnen JT, Moormann RJM, Jongbloed R, van Leen RW, Lubsan NH (1984) The crystallin gene families. In: Nugent J, Whelan J (eds) Human cataract formation. (Ciba Foundation Symposium 106.) Pitman, London, pp208–218

    Google Scholar 

  • Quax-Jeuken Y, Quax W, Meera Khan P, Bloemondal (1985) Complete structure of the αB-crystallin gene: conservation of the exonintron distribution in the two nonlinked α-crystallin genes. Proc Natl Acad Sci USA 82: 5819–5823

    Google Scholar 

  • Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98: 503–517

    Google Scholar 

  • Szybalska EH, Szybalski W (1962) Genetics of human cell lines. IV. DNA-mediated heritable transformation of a biochemical trait. Proc Natl Acad Sci USA 48: 2026–2034

    Google Scholar 

  • Willard HF, Meakin SO, Tsui L-C, Breitman ML (1985) Assignment of human gamma crystallin multigene family to chromosome 2. Somatic Cell Mol Genet 11: 511–516

    Google Scholar 

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Sparkes, R.S., Mohandas, T., Heinzmann, C. et al. Assignment of a human beta-crystallin gene to 17cen-q23. Hum Genet 74, 133–136 (1986). https://doi.org/10.1007/BF00282076

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  • DOI: https://doi.org/10.1007/BF00282076

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