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Interleukin 1

  • Chapter
Growth Factors, Differentiation Factors, and Cytokines

Abstract

Interleukin 1 (IL-1) is the name of two related but distinct polypeptides — IL-1 a and IL-1 β — that bind to the same receptor and have identical biological properties. The term interleukin 1 was introduced in 1979 (Aarden et al. 1979) to describe a product of macrophages that stimulated T cells and B cells but also had non-immunological properties. In contrast, interleukin-2 refers to the lymphocyte product with T-cell stimulating properties.

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Authors
  1. R. Schindler
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  2. C. A. Dinarello
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Editors and Affiliations

  1. Department of Internal Medicine Division of Endocrinology and Metabolism, University of Heidelberg, Bergheimer Straße 58, D-6900, Heidelberg, Germany

    Andreas Habenicht

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Schindler, R., Dinarello, C.A. (1990). Interleukin 1. In: Habenicht, A. (eds) Growth Factors, Differentiation Factors, and Cytokines. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74856-1_7

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  • DOI: https://doi.org/10.1007/978-3-642-74856-1_7

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