Biochemical and Biophysical Research Communications
Volume 249, Issue 3, 28 August 1998, Pages 637-642
Regular ArticleDifferences in Cytotoxicity of Native and Engineered RIPs Can Be Used to Assess Their Ability to Reach the Cytoplasm☆
References (37)
- et al.
J. Biol. Chem.
(1987) - et al.
Biochem. Biophys. Res. Comm.
(1988) - et al.
J. Mol. Biol.
(1992) - et al.
J. Biol. Chem.
(1987) - et al.
J. Biol. Chem.
(1992) - et al.
FEBS Lett.
(1994) - et al.
J. Biol. Chem.
(1993) - et al.
Cell
(1987) - et al.
J. Biol. Chem.
(1984) - et al.
J. Biol. Chem.
(1974)
J. Biol. Chem.
(1985)
Arch. Biochem. Biophys.
(1975)
FEBS Lett.
(1992)
Gene
(1988)
J. Biol. Chem.
(1976)
Biochim. Biophys. Acta
(1976)
Arch. Biochem. Biophys.
(1993)
FASEB Journal
(1994)
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Recombinant pebulin protein, a type 2 ribosome-inactivating protein isolated from dwarf elder (Sambucus ebulus L.) shows anticancer and antifungal activities in vitro
2021, International Journal of Biological MacromoleculesCitation Excerpt :In contrast to plant and bacterial cell-free systems, Ebulin l demonstrates an intense inhibitory activity on protein synthesis in mammalian cells [25]. However, it has been indicated that Ebulin l is significantly less toxic for cultured human T cells than ricin, due to variations in cell binding, membrane translocation, or intracellular routing [26]. The low toxicity of Ebulin 1 in vivo and in vitro compared to ricin led to apply it for the production of immunotoxins and conjugates for tumor therapy [27].
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Parker, M.Landes, R. G.
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